Anti-CSNK2A1 Antibody

CK2 catalytic subunit research often requires a specific, well-validated reagent for both Western blotting and immunohistochemistry workflows. This polyclonal antibody targets CSNK2A1 (casein kinase 2 alpha 1), the catalytic subunit of the ubiquitous CK2 holoenzyme, and is raised in rabbits as an unconjugated IgG preparation. Verified reactivity spans human, mouse, and rat samples, supporting comparative signaling studies across standard model systems and patient-derived tissues.

The casein kinase 2 pathway participates in cell cycle progression, DNA damage response, Wnt signaling, apoptosis regulation, and transcriptional control, so laboratories commonly deploy this antibody when exploring kinase-driven mechanisms in cancer biology, circadian rhythm research, and broader signal transduction projects. The 200 µl vial provided by Antibodies.com accommodates multi-blot screening campaigns and parallel IHC panel work without frequent reordering, and the unconjugated format leaves conjugation chemistry open for custom detection strategies.

Independent characterization confirms recognition of CSNK2A1 in cell lysates and fixed sections, supporting reproducible detection of phosphorylated substrates and CK2 complex partners. Researchers building kinase-focused panels for substrate phosphorylation mapping, therapeutic target validation, or downstream effector analysis will find this Antibodies.com reagent a practical complement to broader phospho-proteomic workflows.