Anti-CSNK2A1 Antibody

CSNK2A1 encodes the catalytic alpha subunit of casein kinase II, a ubiquitously expressed serine/threonine kinase implicated in cell cycle regulation, transcriptional control, apoptosis signaling, and Wnt pathway activity. Aberrant CK2 alpha expression has been documented across multiple cancer types, making this target relevant to oncology, signal transduction, and kinase biology research.

This rabbit polyclonal IgG reagent from Antibodies.com is supplied unconjugated in a 100 µl volume and validated for western blot and immunohistochemistry workflows. Cross-reactivity has been confirmed against human, mouse, and rat samples, supporting translational studies that compare expression across rodent models and human tissue. The polyclonal format increases the likelihood of recognizing multiple epitopes on the CK2 alpha protein, which is useful when probing denatured lysates in WB or fixed tissue sections in IHC.

The antibody is provided as a liquid IgG preparation without an enzymatic or fluorescent tag, so it can be paired with secondary detection reagents of the researcher's choice, including HRP-conjugated, biotinylated, or fluorophore-labeled secondaries, depending on the readout. Researchers studying kinase signaling, proliferation, and stress response pathways frequently use anti-CSNK2A1 antibodies to assess total CK2 alpha levels alongside phospho-specific reagents.