Anti-CSN1S1 Antibody

CSN1S1, also known as alpha-S1-casein, is one of the principal casein fractions that make up mammalian milk and serves as a widely used marker of mammary epithelial differentiation in rodent and livestock lactation models. The polyclonal rabbit reagent offered here is raised against this protein and is supplied by Antibodies.com as 100 µl of unconjugated antiserum prepared in the rabbit host with an IgG isotype.

For researchers studying lactation biology, milk protein composition, and mammary gland development, this CSN1S1 reagent is validated for Western blot analysis of tissue and cell lysates prepared from mouse samples. The polyclonal format broadens epitope coverage compared with monoclonal reagents, which is particularly useful when monitoring shifts in endogenous CSN1S1 levels across lactation stages or in cell culture models of mammary epithelial differentiation. Because the primary antibody is unconjugated, the same vial can be paired with HRP-, biotin-, or fluorophore-conjugated secondary antibodies to suit chemiluminescent or fluorescent detection workflows.

Typical starting material includes whole-cell lysates or mammary gland homogenates from lactating mice. Aliquot on receipt and store the stock at -20°C in single-use portions to limit freeze-thaw cycles; thawed working aliquots kept short term at 4°C retain activity for routine immunoblotting. Preparing aliquots sized to one or two experiments at a time helps preserve titer and avoid the loss of signal that comes from repeated freeze-thaw of the polyclonal preparation.