Anti-CSF1R (phospho Y699) Antibody

This rabbit-derived polyclonal reagent from Antibodies.com targets the Colony Stimulating Factor 1 Receptor (CSF1R), also known as CD115 or M-CSFR, specifically when tyrosine 699 is phosphorylated. Y699 is one of several autophosphorylation sites engaged upon CSF1 ligand binding, and the phospho-specific reagent allows researchers to monitor the activated receptor state separately from total CSF1R protein levels. The antibody is supplied as 100 µl of unconjugated IgG and is validated for Western blot detection of the activated human receptor following ligand stimulation. The reagent is well-suited to studies of macrophage differentiation, osteoclastogenesis, and downstream signalling cascades such as PI3K/AKT and MAPK. Store refrigerated in working aliquots to limit freeze-thaw cycles, and pair with a phosphorylation-independent CSF1R antibody for total receptor comparisons.