Anti-CS Antibody

This rabbit polyclonal antibody targets Citrate Synthase (CS), the mitochondrial matrix enzyme that catalyzes the condensation of acetyl-CoA with oxaloacetate to form citrate in the tricarboxylic acid cycle. Produced by Antibodies.com as an unconjugated primary reagent, the antibody is supplied as 100 µl of liquid and is validated for Western blot, immunohistochemistry, and immunofluorescence workflows across human, mouse, and rat samples.

Because citrate synthase expression scales with mitochondrial mass, the reagent is widely used as a normalization control when quantifying mitochondrial content by Western blot, as a marker in cell culture studies of metabolic reprogramming, and in immunohistochemistry of tissue sections where mitochondrial density is being compared between experimental groups. Polyclonal reactivity against conserved regions of the enzyme supports consistent detection of the target in denatured lysates as well as native conformation in fixed cells and tissue.

Researchers investigating oxidative phosphorylation, the Warburg effect in tumor biology, neurodegeneration, and exercise or metabolic-disease models commonly select Antibodies.com anti-CS preparations for reproducible loading controls and target verification. The unconjugated format gives laboratories flexibility to conjugate the antibody in-house to HRP, fluorophores, or biotin depending on the detection platform.