Anti-CRY1 Antibody

Primary antibody from Antibodies.com raised in rabbit and directed against human CRY1, a core circadian repressor of the CLOCK-BMAL1 transcriptional activator complex. The polyclonal reagent is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a stabilizer, and ships in a 100 µl vial suitable for multiple immunoblots and staining runs. Validated applications include Western blot and immunohistochemistry on human tissue sections. CRY1 (Cryptochrome Circadian Regulator 1) operates within the negative feedback loop that generates 24-hour cellular rhythms, and the unconjugated format allows researchers to pair it with their preferred secondary reporter for fluorescence, chromogenic, or chemiluminescent detection in research use only protocols. Because CRY1 also contributes to DNA damage response signaling, this reagent is useful for studies linking clock biology to genome maintenance in cultured cells and fixed tissue specimens.