Anti-CRTC1 Antibody [Assigned #A9918]

CRTC1 (CREB-regulated transcription coactivator 1, also known as TORC1) is a key transcriptional coactivator of CREB-dependent gene expression, implicated in neuronal long-term memory, glucose homeostasis, and the pathobiology of mucoepidermoid carcinoma where CRTC1-MAML2 gene fusions occur. This mouse monoclonal IgG reagent from Antibodies.com specifically targets CRTC1 and is supplied unconjugated in a 200 µl vial. Validated for Western blotting (WB) and immunocytochemistry (ICC), the antibody shows cross-reactivity across human, mouse, rat, and monkey samples, supporting comparative studies in cell line and primary tissue models. Researchers investigating cAMP/PKA signaling, ER-stress responses, or oncogenic transcriptional programs can use this reagent to detect endogenous CRTC1 protein levels, track nuclear translocation following calcium or forskolin stimulation, and probe the impact of CRTC1 dysregulation in metabolic and oncological research contexts.