Anti-CRTC1 Antibody [Assigned #A9918]

Raised in mouse against the CRTC1 transcription coactivator (also called TORC1 and MECT1), this unconjugated IgG monoclonal is supplied as a 100 µl vial for use in Western blot and immunocytochemistry workflows. CRTC1 partners with CREB1 to drive cAMP-responsive gene expression and has been linked to hepatic gluconeogenesis, neuronal long-term memory formation, and the t(11;19) translocation that generates the CRTC1-MAML2 fusion characteristic of mucoepidermoid salivary gland tumors.

The antibody from Antibodies.com is validated across a reactivity panel that includes human, mouse, rat, and monkey samples, supporting both cell line work and primary tissue studies in oncology and metabolic research. Endogenous CRTC1 protein detection is enabled by the unconjugated format, which is compatible with a user-selected secondary antibody. Recommended handling includes aliquoting upon first use, storage at -20 °C, protection from light, and avoiding repeated freeze-thaw cycles to preserve binding activity through multiple experiments.