Anti-CRMP-2 (Ab-509) Antibody

CRMP-2 (Collapsin Response Mediator Protein 2) is a neuronal phosphoprotein central to axon guidance, microtubule assembly, and neuronal polarity. The Ab-509 epitope corresponds to a threonine 509 phosphorylation site that sits downstream of GSK3β and contributes to neurodevelopmental and neurodegenerative signaling cascades. This unconjugated rabbit polyclonal antibody from Antibodies.com selectively recognizes CRMP-2 phosphorylated at Thr509 and is validated for western blot and immunohistochemistry on human specimens. Provided as 100 µl of polyclonal reagent, it is commonly applied to neuronal cell lysates and brain tissue sections in studies of semaphorin signaling, neurite outgrowth, and cytoskeletal remodeling relevant to Alzheimer's pathology and traumatic brain injury research.