Anti-CRF-RII Antibody

This polyclonal reagent from Antibodies.com recognizes corticotropin-releasing factor receptor 2 (CRF-RII), a class B G protein-coupled receptor that mediates cellular responses to CRF-related peptides including urocortin 1, urocortin 2, and urocortin 3. Raised in rabbit and supplied as an unconjugated 100 µl vial, the antibody is validated for Western blot, immunofluorescence, and ELISA workflows.

Cross-reactivity has been confirmed against human, mouse, and rat samples, supporting comparative studies of HPA-axis regulation, stress signaling, cardiac function, and gastrointestinal motility across rodent and human model systems. Researchers commonly apply the antibody to membrane-enriched lysates and fixed tissue sections where CRF-RII expression patterns can be examined at the protein level, and the unconjugated format allows flexible pairing with secondary reagents of choice.