Anti-CRELD2 Antibody

This polyclonal primary antibody from Antibodies.com targets CRELD2 (Cysteine Rich With EGF Like Domains 2), an endoplasmic reticulum–resident protein implicated in the unfolded protein response and connective tissue homeostasis. Raised in rabbit and supplied as 100 µl of unconjugated antiserum, the reagent is validated for Western blot and immunohistochemistry workflows on human samples, supporting studies of ER stress signaling, cardiac morphogenesis, and extracellular matrix remodeling.

The polyclonal format increases the likelihood of recognizing multiple epitopes across the CRELD2 protein, which helps when probing tissue sections where antigen accessibility varies. Investigators exploring Alzheimer-related proteostasis, Ehlers-Danlos–like connective tissue phenotypes, and stress granule biology have used CRELD2 as a marker of PERK and IRE1 pathway activation. For best results, store the vial refrigerated and protected from light in working aliquots to limit freeze-thaw degradation of the antibody.