Anti-CREB3L2 Antibody

CREB3L2 (cAMP responsive element binding protein 3-like 2) is a membrane-bound transcription factor of the CREB/ATF family that localizes to the endoplasmic reticulum and translocates to the nucleus upon ER stress, where it drives expression of genes involved in collagen biogenesis and the unfolded protein response. This unconjugated rabbit polyclonal IgG reagent from Antibodies.com is raised against CREB3L2 and validated for western blot detection of the endogenous protein in human, mouse, and rat samples, supporting studies of fibrotic disease, ER stress signaling, chondrogenesis, and certain translocation-driven sarcomas in which CREB3L2 gene fusions are of clinical interest. Each vial contains 100 µl of antibody, supplied for research use only.