Anti-CREB1 Antibody [Assigned #A10826]

Targeting the 43 kDa cAMP response element-binding protein (CREB1), this rabbit monoclonal IgG reagent from Antibodies.com provides specific detection of full-length endogenous CREB1 across multiple assay platforms. The unconjugated format supports flexible pairing with user-selected secondary labels, enabling custom detection strategies in immunofluorescence and immunohistochemistry protocols. Clone #A10826 was raised against CREB1 and is validated on human, mouse, and rat samples, providing reliable coverage for cross-species studies of cAMP-dependent transcription downstream of PKA, MAPK, and stress-activated kinase signaling.

Supplied as 200 µl of liquid in a vial, the antibody is prepared for western blot analysis of cell lysates and tissue homogenates, producing a characteristic band at approximately 43 kDa consistent with the predicted molecular weight of the CREB1 protein. Researchers apply this reagent to investigate phosphorylation-dependent gene expression, BDNF transcription in neuronal models, and cAMP-responsive element-driven reporter activity. The reagent tolerates standard aliquoting and storage at -20°C; limiting freeze-thaw cycles preserves binding activity for longitudinal studies of synaptic plasticity, metabolic regulation, and memory-associated signaling cascades.