Anti-CREB (Ab-129 / 133) Antibody

Primary antibody from Antibodies.com targeting cAMP response element-binding protein (CREB) when phosphorylated at Ser129 and Ser133. This rabbit polyclonal reagent is supplied as 100 µl of unconjugated antisera and is validated for western blot (WB) and immunohistochemistry (IHC) applications on human samples. The antibody specifically binds the phosphorylated form of CREB, supporting studies of cAMP/PKA signaling, neuronal transcription, long-term memory formation, and CRE-dependent gene regulation. Researchers use this reagent to investigate how phosphorylation at these residues modulates CREB dimerization, DNA binding, and recruitment of co-activators such as CBP and p300 in both cell and tissue contexts.