Anti-CREB-1 Antibody

Offered through the Antibodies.com catalogue, this mouse monoclonal reagent targets endogenous CREB-1 (cAMP-responsive element-binding protein 1) and is supplied as a 50 µL aliquot at a working concentration of 1 mg/mL. It is raised in a mouse host using a recombinant protein immunogen and purified by affinity chromatography to ensure specific recognition of the native target in both human and mouse samples. The unconjugated antibody is formulated in PBS at pH 7.4 with 0.02% sodium azide as preservative and 50% glycerol, and is shipped on cold packs at 4 °C; on arrival it should be aliquoted and stored at –20 °C, with repeated freeze/thaw cycles avoided to preserve activity. Validated applications on the supplier datasheet cover western blot (WB) and immunohistochemistry (IHC), making the reagent suitable for studying CREB-1 expression and downstream cAMP-dependent transcriptional regulation in tissue lysates and fixed sections. For detection workflows, the manufacturer lists a panel of compatible goat anti-mouse IgG H&L secondaries conjugated to AP, biotin, FITC, or HRP, which can be ordered separately. The product is intended for research use only and is not cleared for diagnostic or therapeutic applications.