Anti-CREB-1 Antibody

This unconjugated mouse monoclonal antibody recognises CREB-1, a cAMP-responsive transcription factor that binds to CRE elements and drives expression of genes involved in neuronal plasticity, glucose homeostasis, and cell survival signalling. Produced by Antibodies.com, it is supplied in a 100 µl volume and is validated for Western blot and immunohistochemistry workflows.

Because the reagent is raised in mouse and detects epitopes shared by human and mouse CREB-1, it supports comparative studies across species using matched cell lines and tissue specimens. For Western blot, it is applied to cell or tissue lysates to confirm CREB-1 expression across experimental conditions, including stimulation of cAMP/PKA signalling pathways. For immunohistochemistry, it enables visualisation of nuclear CREB-1 distribution in fixed sections, supporting mapping of CREB-1 localisation across brain regions, endocrine tissue, and tumour specimens.

The unconjugated format lets laboratories pair the antibody with their preferred secondary detection system, including HRP, biotin, or fluorescent conjugates, according to the assay design. Storage at 4 °C with aliquoting to limit freeze-thaw cycles preserves activity across extended studies.