Anti-CREB-1 Antibody

Produced in rabbit hosts, this unconjugated polyclonal reagent from Antibodies.com is supplied as 100 µl of antiserum validated for western blot, immunohistochemistry, and ELISA across human, mouse, and rat samples. The antibody recognizes CREB-1, a cAMP response element-binding transcription factor central to memory formation, neuronal plasticity, and stress-response signaling pathways.

CREB-1 activity is routinely investigated through its phosphorylation at Ser133, and this reagent is used in neuroscience, oncology, and metabolic disease research to probe cAMP-dependent gene regulation. The polyclonal format offers broader epitope coverage than monoclonal alternatives, which is advantageous when detecting endogenous CREB-1 in primary tissue or monitoring its redistribution between nuclear and cytoplasmic compartments.

Aliquot upon receipt and store refrigerated; avoid repeated freeze-thaw cycles to preserve binding activity. Each vial supports reproducible detection of the 43 kDa transcription factor in cell culture lysates, fixed tissue sections, and recombinant protein preparations.