Anti-CPN1 Antibody

This polyclonal primary antibody from Antibodies.com targets CPN1 (carboxypeptidase N catalytic chain), a zinc-dependent metalloprotease synthesized in the liver and secreted into plasma. The enzyme selectively cleaves C-terminal arginine and lysine residues from circulating peptides, regulating the biological activity of bradykinin, the complement anaphylatoxins C3a and C5a, and fibrin-derived peptide fragments. Researchers investigate CPN1 in settings ranging from complement-driven inflammation and coagulation studies to vasoactive peptide signaling pathways.

Raised in rabbit and supplied as an unconjugated IgG preparation, the reagent is validated for Western blot detection in Human and Mouse-derived samples. The unconjugated format pairs with HRP-conjugated, fluorophore-labeled, or biotinylated secondary reagents of the researcher's choosing, supporting flexible workflow design for protein expression profiling, tissue-lysate characterization, and subcellular fractionation experiments aimed at quantifying CPN1 abundance.

Aliquot upon arrival and store frozen at -20 °C; brief storage at 4 °C is appropriate for short-term working stocks. Protect from light and limit freeze-thaw cycles to preserve binding activity across longer studies. The 100 µl volume accommodates multiple Western blot experiments on standard mini-gel formats.