Anti-CPD Antibody

Produced in rabbit, this unconjugated polyclonal antibody from Antibodies.com targets Carboxypeptidase D (CPD), a zinc-dependent metallocarboxypeptidase that trims C-terminal arginine and lysine residues from peptide substrates within the secretory pathway. Each 100 µl vial is supplied at 1 mg/ml in phosphate buffered saline (PBS) with 15 mM sodium azide at approximately pH 7.2, ready to dilute directly into Western blot workflows. Validated reactivity across human, mouse, and rat samples makes the reagent useful for comparative studies of CPD expression in different tissue or cell models. CPD is broadly expressed and has been linked to the proteolytic maturation of pro-hormones, growth factors, and other bioactive peptides transiting the trans-Golgi network. The polyclonal format increases the likelihood of recognizing multiple epitopes on the CPD polypeptide, which is helpful when working with denatured samples on reducing SDS-PAGE. Sodium azide serves as a microbial preservative; for applications where azide may interfere, aliquot the antibody and store frozen. The format suits standard chemiluminescent Western blot detection on nitrocellulose or PVDF membranes following transfer of resolved proteins.