Anti-COX6C Antibody

Sourced through Antibodies.com, this affinity-purified reagent is a Rabbit polyclonal antibody raised against COX6C (cytochrome c oxidase subunit 6C), a nuclear-encoded component of mitochondrial complex IV. The immunogen is a synthesized peptide derived from the internal region of human COX6C, and the antibody has been purified from rabbit antiserum by affinity-chromatography using the epitope-specific immunogen, ensuring selective recognition of endogenous COX6C. Supplied at 50 µl per vial at a working concentration of 1.0 mg/mL, the product is formulated as Rabbit IgG in phosphate-buffered saline (without Mg²⁺ and Ca²⁺) at pH 7.4, supplemented with 150 mM NaCl, 0.02% sodium azide as a preservative, and 50% glycerol for cryoprotection. The conjugate is unconjugated, leaving the primary antibody free for downstream labelling or detection chemistries of the user's choice. Validated applications include Western blotting (WB) and immunocytochemistry/immunofluorescence (ICC/IF), and reactivity has been confirmed in Human, Mouse, and Rat samples, making this reagent suitable for cross-species mitochondrial respiratory chain studies. The polyclonal format offers an epitope-spread advantage for detecting COX6C under varying expression levels, while the host species (Rabbit) and IgG isotype are broadly compatible with common secondary reagents. This Primary Antibody is part of the Antibodies.com catalogue and is dispatched in temperature-protected packaging from St. Louis, MO, with a typical lead time of 6–9 business days. Researchers working on oxidative phosphorylation, mitochondrial biogenesis, or complex IV assembly can use this reagent to probe steady-state levels of COX6C in cultured cells and tissue lysates by WB, or to visualize its subcellular distribution by ICC/IF, given the protein's well-characterized mitochondrial localization.