Anti-COX6B1 Antibody

A rabbit polyclonal reagent from Antibodies.com that targets COX6B1, the nuclear-encoded mitochondrial subunit of cytochrome c oxidase (respiratory chain complex IV). The unconjugated primary antibody is supplied at 100 µl in a vial and is validated for Western blot, immunohistochemistry, and immunofluorescence workflows on human samples.

COX6B1 contributes to the assembly and stability of complex IV, the terminal enzyme of the electron transport chain that reduces molecular oxygen and drives proton translocation across the inner mitochondrial membrane. Researchers studying mitochondrial biology, oxidative phosphorylation, and related metabolic or neurodegenerative pathways use this reagent to probe COX6B1 protein expression in cultured human cells and fixed tissue sections.

For immunofluorescence, the antibody is applied to visualize mitochondrial COX6B1 distribution; for Western blot, it detects the protein at its expected size; and for IHC, it supports localization studies on formalin-fixed paraffin-embedded tissue. The polyclonal format provides broader epitope coverage, and the unconjugated format allows flexible pairing with secondary antibodies labelled to the user's preferred fluorophore or enzyme. Store refrigerated in working aliquots to limit freeze-thaw cycles, and protect from light when handling conjugated secondaries.