Anti-COX6A2 Antibody

This polyclonal antibody from Antibodies.com targets COX6A2, the mitochondrially-encoded cytochrome c oxidase subunit 6A2, a heart- and skeletal-muscle-enriched component of respiratory chain complex IV. Raised in rabbit and supplied as an unconjugated IgG preparation in a 100 µl vial, the reagent has been validated for Western blot detection of the human protein and for immunohistochemistry on fixed tissue sections. COX6A2 (also called COX VIa-H or subunit VIa polypeptide 2) replaces the paralogous COX6A1 isoform in contractile muscle mitochondria and contributes to the catalytic core assembled around MT-CO1 and MT-CO2. Researchers studying mitochondrial bioenergetics, oxidative phosphorylation disorders, or muscle-specific metabolic specialization use this antibody to assess steady-state subunit levels, track complex IV assembly intermediates, and compare isoform expression between striated muscle and other tissues. The reagent is for research use only, and aliquoting upon arrival is recommended to limit freeze-thaw cycles and preserve titer for downstream western blot and immunohistochemistry workflows.