Anti-COX5B Antibody

The Antibodies.com polyclonal reagent targets COX5B, the B isoform of cytochrome c oxidase subunit 5, a nuclear-encoded component of mitochondrial respiratory chain complex IV that contributes to oxidative phosphorylation in human cells. Raised in rabbit and supplied as an unconjugated antiserum, this Primary Antibodies reagent is validated for Western Blot (WB) and Immunohistochemistry (IHC), supporting protein-level studies of mitochondrial bioenergetics, OXPHOS subunit assembly, and respiratory chain remodeling in human tissue and cell-line samples.

Packaged as a 100 µl aliquot, the antibody is suited to probing steady-state COX5B levels across multiple sample types, including paraffin-embedded sections for IHC and standard SDS-PAGE lysates for WB. Researchers investigating mitochondrial dysfunction, metabolic disorders, hypoxia response, or cytochrome c oxidase biogenesis can use this reagent to characterize expression changes in patient-derived material or experimental models.

Recommended starting dilutions should be optimized for each specific application, detection chemistry, and sample preparation. Store refrigerated to preserve activity across the working shelf life, and avoid repeated freeze-thaw cycles by aliquoting on first use. The reagent is intended for research use only and is not validated for diagnostic or therapeutic applications.