Anti-COX15 Antibody

COX15 is a mitochondrial inner membrane protein essential for cytochrome c oxidase (complex IV) assembly and heme A biosynthesis. This rabbit polyclonal antibody from Antibodies.com targets the COX15 protein and is validated for Western blot (WB) detection in human, mouse, and rat samples. The unconjugated reagent is supplied as 100 µL at 1 mg/mL in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.3, supporting flexibility in downstream secondary antibody pairing and detection chemistry.

COX15 functions as a heme A synthase, and loss-of-function mutations in the gene have been linked to mitochondrial complex IV deficiency. Investigators studying mitochondrial respiratory chain disorders, oxidative phosphorylation, or heme biosynthesis use this reagent to probe COX15 expression across mammalian model systems. For short-term use, store at 4 °C; for extended storage, aliquot and freeze to preserve activity across multiple freeze-thaw cycles, and protect from light to maintain formulation integrity.