Anti-COX11 Antibody

From Antibodies.com, this rabbit polyclonal IgG antibody targets the mitochondrial inner membrane assembly factor COX11, the protein product of the human COX11 gene required for copper incorporation into the COX1 subunit of cytochrome c oxidase (complex IV) during oxidative phosphorylation biogenesis. The unconjugated, polyclonal IgG preparation is supplied as a 100 µl vial and is validated for western blot (WB) detection of the human target in cell lysates and tissue homogenates.

Researchers investigating mitochondrial respiratory chain assembly, copper trafficking into respiratory complexes, or inherited mitochondrial disorders use this reagent to probe endogenous COX11 protein. The polyclonal format raises antibodies against multiple epitopes, which often improves recognition of low-abundance mitochondrial proteins compared with monoclonal alternatives. The unconjugated format gives flexibility to pair the antibody with HRP-, fluorophore-, or biotin-conjugated secondary reagents for individual experimental designs.

For handling, store refrigerated; aliquot upon first use to minimize freeze-thaw cycles and protect from light. The reagent is intended for research use only.