Anti-Corticosterone Antibody

This mouse-derived monoclonal reagent from Antibodies.com is raised against corticosterone and supplied as a Protein G purified antibody in unconjugated form, giving researchers flexibility to conjugate the antibody with HRP, biotin, or fluorescent reporters as their detection chemistry requires. The IgG2b isotype clone has been validated for ELISA workflows, supporting immunoassay development targeting the dominant rodent glucocorticoid hormone. Each vial contains 1 mg of purified antibody, sufficient for many microplate-scale experiments. Corticosterone quantification underpins stress axis research, including studies of the hypothalamic-pituitary-adrenal (HPA) axis, circadian variation in glucocorticoid secretion, and behavioral paradigms involving fear, anxiety, or learning and memory. Because the antibody is unconjugated, end users can choose direct or indirect detection formats and titrate labeling density to match their particular assay sensitivity requirements. For handling, aliquot upon receipt and refrigerate the working solution; protect from light when handling the reconstituted material to preserve antibody integrity across repeated uses. The monoclonal format provides lot-to-lot consistency that polyclonal corticosterone reagents cannot match, which is particularly valuable when comparing hormone measurements across longitudinal rodent studies or between experimental cohorts.