Anti-Cortactin Antibody

This unconjugated rabbit polyclonal reagent from Antibodies.com targets cortactin, an actin-binding regulator of cytoskeletal dynamics involved in cell migration, lamellipodia formation, and invadopodia assembly. Cortactin localizes to sites of dynamic actin remodeling, where it cooperates with the Arp2/3 complex to drive branched actin network formation. Researchers studying cancer cell invasion, receptor endocytosis, and signal transduction pathways use this reagent to probe cortactin expression across multiple model systems. Supplied as 100 µl of polyclonal antibody in a vial format, the antibody is validated for WB and ELISA applications and shows reactivity with Human, Mouse, and Rat samples. The polyclonal nature of the reagent provides broad epitope coverage, which is useful when working with post-translationally modified or alternatively spliced cortactin isoforms. The unconjugated format offers flexibility in downstream detection, allowing researchers to pair the antibody with their preferred secondary reagents and to choose chromogenic, chemiluminescent, or fluorescent imaging modalities according to experimental needs.