Anti-COPS5 Antibody

COPS5 (also called JAB1) is the fifth subunit of the COP9 signalosome, a conserved multi-protein complex that controls c-Jun-driven transcription, cell cycle progression, and protein ubiquitination. This Antibodies.com polyclonal reagent was raised in rabbit and is provided unconjugated in a 50 µl vial. It is validated for Western blot (WB) and immunohistochemistry (IHC) and shows reactivity with human, mouse, and rat samples, supporting cross-species research in cancer biology, DNA damage response, and signal transduction. For best results, store at -20°C and prepare working aliquots to limit freeze-thaw cycles; thaw on ice before use. The antibody detects endogenous COPS5 in whole-cell lysates and tissue sections, making it a practical tool for studies of transcription factor regulation, downstream targets such as c-Jun and p27, and the broader COP9 signalosome pathway.