Anti-COPS5 Antibody

This rabbit polyclonal antibody recognizes COPS5, the catalytic subunit of the COP9 signalosome complex also known as CSN5 or Jab1, and is supplied by Antibodies.com as an unconjugated primary reagent. The immunogen design targets epitopes conserved across human, mouse, and rat orthologs, enabling detection in standard western blot and immunohistochemistry workflows. Each vial contains 100 µl of liquid antibody, and aliquoting into working stocks on first use is recommended. Storage guidance is to refrigerate at 4 °C for short-term use; for longer-term storage, freeze at -20 °C in working aliquots to limit freeze-thaw cycles and preserve binding activity. Researchers commonly apply this reagent to investigate c-Jun N-terminal kinase signaling, p53 and c-Jun regulatory pathways, and ubiquitin-proteasome crosstalk in cancer biology and developmental studies. The polyclonal format offers broader epitope coverage than monoclonal alternatives, useful when studying post-translational modifications or splice variants of COPS5 in cell lysates and fixed tissue specimens.