Anti-COPS4 Antibody

COPS4 is the fourth subunit of the COP9 signalosome, a multi-protein complex that regulates the ubiquitin-proteasome degradation pathway and modulates cullin-RING E3 ligase activity through deneddylation of cullins. This unconjugated polyclonal reagent from Antibodies.com is raised in rabbit hosts, purified as IgG, and validated for Western blot detection of endogenous COPS4 expression in human, mouse, and rat samples. Supplied as a 100 µl liquid aliquot, the antibody supports investigation of COP9 signalosome assembly, cullin neddylation status, and proteasome-mediated protein turnover in whole-cell lysate preparations. Researchers should follow standard storage and handling guidance, including aliquoting upon receipt to limit freeze-thaw cycles and preserve reagent activity across multiple blotting experiments.