Anti-COPS3 Antibody

This polyclonal reagent from Antibodies.com targets COPS3, a core component of the COP9 signalosome complex that regulates cullin deneddylation, ubiquitin-dependent protein turnover, and cell cycle progression. Raised in rabbit and supplied as an unconjugated preparation at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the antibody is delivered in a 100 µl vial format. It has been validated for western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF) applications, with reactivity confirmed against human, mouse, and rat samples. The polyclonal clonality enables recognition of multiple epitopes across the COPS3 subunit, supporting detection in both denatured lysates and fixed tissue specimens. The reagent is suited to research on COP9 signalosome assembly, deneddylation activity, and downstream ubiquitin-mediated protein degradation pathways.