Anti-Connexin 43 (phospho-S367) Antibody

The Antibodies.com polyclonal antibody targets Connexin 43 phosphorylated at serine 367, a post-translational modification that regulates gap junction gating, assembly, and internalization in response to kinase signaling.

Supplied as 100 µl of unconjugated rabbit polyclonal IgG at 1 mg/ml in phosphate buffered saline (pH 7.2) with 15 mM sodium azide as preservative, the reagent is validated for western blot and immunohistochemistry workflows.

Reactivity has been confirmed against human, mouse, and rat samples, making the antibody useful for cross-species studies of cardiac, neural, and epithelial tissues where connexin-mediated intercellular communication is under investigation.

Phospho-S367 is recognized by protein kinase A and casein kinase 1, and detection of this modified residue supports research into arrhythmia mechanisms, wound healing, and tumor microenvironment signaling.