Anti-Connexin-26 Antibody

Raised in rabbit and affinity-purified by epitope-specific immunogen chromatography, this unconjugated polyclonal reagent from Antibodies.com is designed to detect endogenous levels of Connexin-26 (also known as Cx26, GJB2, or Gap junction beta-2 protein). The immunogen is a synthesized peptide derived from the internal region of the human Connexin-26 sequence, and the resulting IgG antibody is supplied as 50 µl of liquid at a working concentration of 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. It is validated for Western blot (WB) and ELISA applications, and has been confirmed to react with human, mouse and rat samples, making it a versatile choice for cross-species studies of gap junction biology in cochlear, epidermal and hepatic research models. The reagent is shipped at 4°C and should be aliquoted upon arrival and stored at -20°C, with repeated freeze/thaw cycles avoided to preserve activity. Each lot is intended for research use only and is not validated for diagnostic or therapeutic applications, and it is available from supplier AFMS at 1365.0 SAR for the 50 µl format. As a polyclonal, unconjugated reagent, it can be paired with a wide range of secondary antibodies and is well suited to standard immunoblotting and ELISA workflows in laboratories investigating connexin-mediated cell-cell communication, hearing loss associated with GJB2 mutations, or epithelial barrier function.