Anti-COMMD1 Antibody

Raised in rabbit and affinity-purified, this unconjugated polyclonal reagent recognizes COMMD1, the copper metabolism Murr1 domain-containing protein involved in hepatic copper excretion, NF-κB signaling, and regulation of HIF-1α stability. Supplied as a 100 µL vial at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotectant, the antibody from Antibodies.com is validated for western blot detection of endogenous human COMMD1, immunohistochemistry on formalin-fixed tissue sections, and immunofluorescence imaging of cultured cells. Researchers studying Wilson disease pathways, copper transport disorders, or inflammatory signaling cascades can use this reagent to probe COMM domain-mediated protein-protein interactions, ubiquitination-linked turnover, and subcellular localization in relevant cell and tissue models.