Anti-COLQ Antibody

Produced by Antibodies.com as a rabbit polyclonal reagent, this unconjugated IgG antibody recognizes the collagen-like tail subunit of asymmetric acetylcholinesterase (COLQ) and is supplied at a working volume of 50 µl. It is validated for western blot detection of the COLQ target in mouse and rat tissue and cell-derived samples.

COLQ encodes the collagenic tail that anchors acetylcholinesterase to the basal lamina at the neuromuscular junction, supporting cholinergic transmission at peripheral synapses. Researchers investigating congenital myasthenic syndrome arising from COLQ mutations, endplate acetylcholine receptor clustering, and cholinesterase anchoring biology use anti-COLQ antibodies to profile expression in rodent neural and muscular tissues.

Each antibody vial is provided as a 50 µl liquid aliquot intended for use as an unconjugated primary antibody, paired with a compatible anti-rabbit secondary reagent for chemiluminescent western blot readout. Standard cold-chain handling applies, with the polyclonal reagent stored frozen in working aliquots to limit freeze-thaw cycles and preserve binding performance across multiple experimental runs.