Anti-COLEC11 Antibody

This polyclonal antibody reagent from Antibodies.com targets human collectin kidney protein 1 (CL-K1), a secreted pattern-recognition molecule of the innate immune lectin complement pathway encoded by the COLEC11 gene. Raised in rabbit as an unconjugated IgG preparation, the antibody is validated for western blot, immunohistochemistry, and flow cytometry workflows on human samples.

COLEC11 is expressed in liver, kidney, adrenal gland, and several mucosal epithelia, where CL-K1 participates in carbohydrate-dependent pathogen recognition and collaborates with MASP proteases to initiate complement activation through the lectin route. Researchers studying 3MC syndrome, complement pathway dysregulation, mucosal immunity, and developmental craniofacial and skeletal conditions use this reagent to detect endogenous COLEC11 in tissue sections, lysates, and primary cell preparations.

Each vial is supplied as 200 µL of ready-to-titer stock for research use only, intended for laboratory professionals investigating collectin family biology, innate immune surveillance, and rare developmental disorders linked to COLEC11 loss-of-function variants.