Anti-COL5A2 Antibody

COL5A2 encodes the alpha-2 chain of type V collagen, a fibrillar collagen that co-assembles with COL5A1 to regulate fibril diameter in connective tissues including skin, tendon, bone, cornea, and placenta. Mutations in this gene are linked to classic Ehlers-Danlos syndrome, making the protein a frequent target in connective tissue and fibrosis research.

The Antibodies.com reagent is a rabbit polyclonal antibody supplied in a 100 µl vial at 1 mg/ml in phosphate buffered saline (PBS) with 15 mM sodium azide at approximately pH 7.2. Unconjugated and validated for Western blot detection in human and rat samples, the polyclonal reagent recognizes multiple epitopes across the target protein, supporting reproducible band identification in fibroblast lysates, tissue homogenates, and disease model systems.

For storage, keep aliquots frozen at -20°C, avoid repeated freeze-thaw cycles, and protect from light. The rabbit host format enables robust signal generation across a broad molecular weight range appropriate for full-length procollagen chains and processed collagen fragments.