Anti-COL1A1 Antibody

This rabbit polyclonal reagent from Antibodies.com is raised against COL1A1, the gene product that forms the pro-alpha1(I) chain of type I collagen — the dominant fibrillar collagen of vertebrate extracellular matrix and a primary structural constituent of bone, dermis, tendon, ligament, sclera, cornea, and interstitial connective tissues.

Supplied as 100 µl of unconjugated antibody at 1 mg/ml in phosphate buffered saline (PBS) with 15 mM sodium azide, adjusted to approximately pH 7.2. Polyclonal sera typically recognise several independent epitopes along the COL1A1 chain, supporting robust signal in western blot workflows against human, mouse, and rat samples.

Common research contexts include dermal and bone matrix biology, fibrotic disease modelling, osteogenesis imperfecta and Ehlers-Danlos syndrome pathway studies, tumour microenvironment desmoplasia, scar-tissue analysis, and tissue-engineering scaffolds where type I collagen deposition is quantified or tracked.

Handling: aliquot upon receipt to limit freeze-thaw cycles; store refrigerated for routine use; protect from light.