Anti-COL18A1 Antibody

COL18A1 encodes the alpha-1 chain of type XVIII collagen, a basement membrane collagen that serves as the precursor to endostatin, a potent endogenous angiogenesis inhibitor. Mutations in this gene are linked to Knobloch syndrome, a disorder characterized by ocular abnormalities and occipital encephalocele.

This unconjugated rabbit polyclonal IgG antibody from Antibodies.com is raised against COL18A1 and validated for Western blot (WB) applications across human, mouse, and rat samples. Supplied as 200 µl of reagent, the antibody is suited for researchers investigating extracellular matrix biology, tumor angiogenesis, vascular basement membrane remodeling, and inherited connective tissue disorders. The polyclonal format provides recognition of multiple epitopes on the COL18A1 protein, supporting detection in cell lysates and tissue extracts.