Anti-COL11A2 (P1232) Antibody

This polyclonal antibody from Antibodies.com targets the phospho-region surrounding P1232 of human Collagen Type XI Alpha 2 (COL11A2), a fibrillar collagen component linked to Stickler syndrome type III, otospondylomegaepiphyseal dysplasia, and several non-syndromic forms of sensorineural deafness. It is raised in rabbit and purified as an IgG polyclonal reagent, supplied at 1 mg/mL in phosphate-buffered saline (pH ~7.2) containing 0.05% sodium azide. The 50 µL vial is unconjugated and has been validated for Western blot and immunohistochemistry on human and mouse samples, making it a practical choice for studies of collagen fibrillogenesis, skeletal biology, and auditory neuroscience. The reagent specifically detects endogenous COL11A2 protein, with an expected molecular weight of approximately 172 kDa. For optimal stability, it should be kept at 4 °C for short-term use, while long-term storage at −20 °C as aliquots is recommended to avoid repeated freeze-thaw cycles. Intended for research use only, this Antibodies.com reagent offers reliable cross-reactivity with both species most commonly used as models for COL11A2-related disorders.