Anti-COL11A2 (P1232) Antibody

This rabbit polyclonal reagent from Antibodies.com specifically recognizes the COL11A2 protein, the alpha-2 chain of type XI collagen that contributes to fine collagen fibril assembly in cartilage and other connective tissues. Supplied as 100 µl of unconjugated antibody at 1 mg/ml in PBS with 0.05% sodium azide (pH ~7.2), it is validated for Western blot (WB) and immunohistochemistry (IHC) on human and mouse samples. Researchers studying COL11A2 mutations linked to Stickler syndrome type III, otospondylomegaepiphyseal dysplasia, and non-syndromic hearing loss commonly use such reagents to map type XI collagen distribution in articular cartilage, the nucleus pulposus of the intervertebral disc, and cochlear tissue. The polyclonal format increases the likelihood of detecting multiple epitopes on the target, which is useful when probing fixed tissue sections or denatured lysates. Keep the vial refrigerated for routine use; for longer-term storage, aliquot and freeze to preserve activity across repeated freeze-thaw cycles. For research use only.