Anti-COL11A1 Antibody

This unconjugated rabbit polyclonal antibody targets the collagen type XI alpha 1 (COL11A1) chain, a fibril-forming collagen associated with cartilage extracellular matrix assembly and connective tissue disorders such as Stickler syndrome type II and fibrochondrogenesis. From Antibodies.com, the reagent is supplied as a 100 µl vial of liquid and is reactive with human and mouse samples, supporting studies in orthopaedic research, fibrosis models, and oncology where elevated COL11A1 expression has been reported as a cancer-associated fibroblast signature in pancreatic and ovarian tumour tissue.

Validated applications include western blot for protein-level detection of the alpha 1(XI) chain, immunohistochemistry on formalin-fixed tissue sections, immunofluorescence for subcellular localisation, and ELISA for quantitative work. The host species is rabbit, the clonality is polyclonal, and the conjugate is unconjugated, allowing flexible secondary antibody pairing with chromogenic, fluorescent, or HRP-based detection platforms in basic and translational research use only workflows.