Anti-COASY Antibody

COASY (Coenzyme A Synthase) is a bifunctional mitochondrial enzyme bearing both phosphopantetheine adenylyltransferase and dephospho-CoA kinase domains, which together catalyze the final two steps of coenzyme A biosynthesis from pantothenate. This rabbit polyclonal antibody from Antibodies.com was raised against the COASY target and is validated for Western blot detection of the endogenous human and mouse protein in research samples.

Supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the unconjugated IgG allows flexible pairing with HRP-, fluorophore-, or biotin-conjugated secondary reagents. The 50 µl vial format supports multiple immunoblots, and storage at -20 °C in single-use aliquots is recommended to limit freeze-thaw cycles. Investigators studying mitochondrial CoA metabolism, pantothenate pathway flux, or neurodegeneration with brain iron accumulation (NBIA type 6, also known as CoPAN, in which COASY mutations have been linked to disease) will find this reagent useful for expression and localization studies.