Anti-CNTFR Antibody

Produced in rabbits and affinity-purified against the Ciliary Neurotrophic Factor Receptor alpha subunit, this unconjugated polyclonal reagent detects CNTFR across human, mouse and rat sample origins. From Antibodies.com, the antibody is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, packaged in a 100 µl vial that should be stored at -20 degrees C in small aliquots to limit freeze-thaw cycles. Researchers apply it in western blot and immunohistochemistry workflows probing CNTFR expression in neuronal, glial and muscle-lineage tissues, where the receptor anchors the CNTF signaling complex together with gp130 and LIFR-beta to drive JAK/STAT pathway activation. Polyclonal reactivity broadens epitope coverage relative to monoclonal alternatives, which is useful when the target is expressed at low levels or when endogenous post-translational modifications vary between preparations. The reagent is intended for research use only and is not validated for diagnostic or therapeutic applications.