Anti-CNP Antibody

CNP (2',3'-cyclic nucleotide 3'-phosphodiesterase) is a myelin-associated enzyme expressed in oligodendrocytes and Schwann cells, and the polyclonal antibody from Antibodies.com recognizes this target for neuroscience research workflows. Raised in rabbit as an unconjugated IgG reagent, the antibody is validated for Western blot and shows cross-reactivity with human, mouse, and rat samples, supporting comparative studies of central and peripheral nervous system myelination. Supplied as 100 µl of liquid antiserum, it is ready for standard immunoblotting protocols that resolve the characteristic CNP protein band in tissue lysates and cultured cell extracts. Researchers investigating demyelination models, myelin repair mechanisms, oligodendrocyte differentiation, or Schwann cell biology routinely probe for CNP to assess myelin integrity and confirm lineage commitment. Because the reagent is polyclonal, it binds multiple epitopes on CNP, which often improves signal strength in Western blot when sample antigen is partially denatured, and complements monoclonal clones used in parallel staining experiments. Storage guidance for liquid polyclonal preparations typically includes aliquoting upon arrival, avoiding repeated freeze-thaw cycles, refrigerating for short-term use, and protecting from light to preserve binding activity across many experiments.