Anti-CNN2 Antibody

This rabbit polyclonal reagent targets Calponin 2 (CNN2), a 34 kDa actin-associated regulatory protein expressed across smooth muscle and non-muscle tissues, where it modulates cytoskeletal dynamics and contractile function. Produced by Antibodies.com, the unconjugated antibody is raised in rabbit hosts and validated for western blot and immunofluorescence workflows on human and mouse samples. Each vial ships as a 100 µl liquid aliquot in an unconjugated format that pairs with a secondary antibody of the researcher's choice for fluorescence, HRP, or biotin detection chemistries. Applications include western blot for expression profiling, where the target migrates near its predicted molecular weight on SDS-PAGE gels, and immunofluorescence of fixed cells to examine subcellular localization and cytoskeletal association. The reagent supports investigations of vascular smooth muscle differentiation, actin filament remodeling, cell migration mechanics, and fibrosis-related signaling pathways. For best results, aliquot the antibody upon arrival and store frozen, avoiding repeated freeze-thaw cycles to preserve binding activity across long-term experiments. Lot-level quality control confirms reactivity against human and mouse tissue, making this research use only reagent a versatile tool for cell biology, vascular biology, and cardiovascular research laboratories.