Anti-CMTM3 Antibody

This rabbit polyclonal antibody targets CMTM3 (CKLF-like MARVEL transmembrane domain-containing 3), a transmembrane protein implicated in epithelial immune regulation, chemokine signaling, and tumor suppression across multiple tissue types. Produced in rabbit and supplied as an unconjugated IgG preparation, the reagent from Antibodies.com is validated for western blot (WB) and immunohistochemistry (IHC). The antibody shows reactivity with CMTM3 from human, mouse, and rat samples, supporting comparative studies and cross-species tissue work. Delivered as a 200 µl liquid aliquot, the polyclonal format recognizes multiple epitopes on the target, which is informative when working with denatured lysates or fixed tissue sections. CMTM3 has been studied in the context of hepatocellular carcinoma, gastric cancer, and immune cell regulation, where its downregulation has been linked to tumor progression and altered chemokine activity. The antibody detects endogenous CMTM3 in whole-cell lysates for western blot applications, while for IHC it enables visualization of CMTM3 distribution in formalin-fixed paraffin-embedded specimens. Keep refrigerated; aliquot for long-term storage to limit freeze-thaw cycles. Intended for research use only, the reagent supports laboratory investigation of CMTM3 biology and its involvement in disease pathways.