Anti-CMPK1 Antibody

This polyclonal rabbit IgG antibody from Antibodies.com targets CMPK1, the mitochondrial UMP-CMP kinase that drives the final phosphorylation steps in pyrimidine nucleotide salvage pathways. Produced by immunizing rabbits with CMPK1 antigen, the unconjugated reagent is supplied as 200 µL of ready-to-dilute stock and is validated for western blot and immunohistochemistry workflows. Antibody reactivity has been confirmed against both human and mouse samples, supporting its use in translational research projects that compare orthologous tissue specimens or engineered cell models.

Because CMPK1 supports mitochondrial dNTP pools, researchers studying mitochondrial DNA replication, nucleoside analogue metabolism, or nucleotide biosynthesis often use this reagent to track protein expression in cell lysates (WB) and to localize the enzyme within tissue sections (IHC). Refrigerate the vial and minimize freeze-thaw cycles to preserve antibody activity across multiple experiments. The polyclonal format recognizes multiple epitopes on CMPK1, which can improve detection sensitivity across denatured and partially folded protein preparations.