Anti-CMA1 Antibody

Produced in rabbit as a polyclonal IgG preparation, the Anti-CMA1 Antibody from Antibodies.com targets Chymase 1 (CMA1), a chymotrypsin-like serine protease stored in mast cell secretory granules and best known for converting angiotensin I to angiotensin II in cardiovascular and inflammatory contexts. Supplied unconjugated at 100 µl, the reagent is validated for Western blot detection of the human and mouse target, supporting studies of mast cell biology, vascular remodeling, and protease signaling in tissue lysates.

The reagent recognizes endogenous CMA1 expressed by mast cells and is suitable for researchers probing chymase activity, allergic inflammation models, and cardiac or dermal tissue homeostasis. Its polyclonal profile enables recognition of multiple epitopes on the mature protease, and the unconjugated format gives laboratories the flexibility to couple it to HRP, biotin, or fluorophores of their choice for downstream detection.