Anti-CLPS Antibody

Colipase anchors pancreatic lipase to lipid-water interfaces in the duodenum, where it enables triglyceride hydrolysis despite the presence of bile salts. This unconjugated polyclonal IgG reagent from Antibodies.com detects the human and mouse CLPS protein for western blot and immunofluorescence workflows. Supplied at 200 µl volume, it is intended for endogenous expression studies in pancreatic acinar cell preparations and exocrine tissue sections.

As an unconjugated primary antibody, it is compatible with both enzyme- and fluorophore-conjugated secondary reagents, supporting flexible membrane-based or fluorescence-based detection protocols. The rabbit host species and polyclonal clonality suit researchers performing mechanistic studies of dietary fat absorption, pancreatic exocrine function, and lipase cofactor biology. Long-term storage in refrigerated single-use aliquots protects activity across the shelf life, and the vial should be equilibrated to room temperature briefly before each application.

CLPS detection in mouse models and human samples yields expected molecular-weight bands in western blot and cytoplasmic staining patterns in immunofluorescence, consistent with the secreted cofactor's natural distribution in pancreatic acinar cells. Researchers should avoid repeated freeze-thaw cycles by preparing aliquots at first use, and protect from light to preserve antibody integrity over the shelf life. Each vial supports multiple experimental replicates when aliquoted into single-use portions to minimize cross-contamination across independent runs.